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Examples of this phenomenon include CD spectra induced on binding of bilirubin to bovine serum albumin and of dicumarol derivatives to -1 acid glycoprotein The second major class of biopolymers which has been studied by CD is the nucleic acids Of the nucleotide s structural components, only the pentose sugar is chiral Mainly as a result of the presence of this sugar, nucleotides are intrinsically chiral structures and give measurable, albeit weak, CD spectra As the level of structural order increases, however (eg polymerization of nucleotides into polynucleotides followed by assembly into duplex structures such as double-stranded DNA and tRNA), the asymmetry of the system and hence the strength of the CD spectrum obtained also increases CD is therefore a useful measure of structure in nucleic acids.

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(2005) Ethnic variation in validity of classi cation of overweight and obesity using self-reported weight and height in American women and men: the Third National Health and Nutrition Examination Survey Nutrition Journal, 4, 27 Huxley, R et al (2008) The Obesity in Asia Collaboration Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension Obesity Reviews, 9 (Suppl 1), 53 61 Impact Assessment Report accompanying the White Paper from the European Commission (2007) A Strategy For Europe On Nutrition, Overweight and Obesity Related Health Issues (Com(2007) 279 Final Sec(2007) 707) wwweceuropaeu/health/ph_ determinants/life_style/nutrition/documents/ nutrition_impact_enpdf (accessed 28 June 2008) International Obesity Task Force (2005) EU Platform Brie ng Paper March Available as download from wwwiotforg/media/euobesity3pdf (accessed 28 June 2008) James, WP, Chunming, C and Inoue, S (2002) Appropriate Asian body mass indices Obesity Reviews, 3 (3), 139.

Differences are observed in CD spectra due to variation of nucleotide sequence, GC composition, stacking of bases in different forms of DNA (ie A-, B- and Z-DNA), formation of macromolecular assemblies such as ribosomes and nucleosomes and ligand binding to DNA As with proteins, induced CD is also possible with DNA such as when anthracene-9-carbonyl-N 1 -spermine binds to oligonucleotides of de ned sequence Many chromophores associated with biomacromolecules are themselves chiral and CD measurements of their spectra can give information on their interactions with proteins, DNA or macromolecular complexes 356 Linear Dichroism (LD).

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the increase in the backward radiation arises from both the embedded slots in the ground plane and the decreased ground-plane size in wavelength units. In summary, in addition to the lowered resonant frequency, which leads to a possible antenna size reduction, the antenna studied also has widened impedance bandwidth and enhanced antenna gain, which are advantages over compact designs with a slotted radiating patch.

James, WPT, Jackson-Leach, R, Ni Mhurchu, C et al (2004) Comparative quanti cation of health risks: Global and regional burden of disease attributable to selected major risk factors, Vol 1 Ezzati, M, Lopez, A, Roger, A and Murray, C (eds) WHO: Geneva, pp 495 596 Kamadjeu, RM, Edwards, R, Atanga, JS et al (2006) Anthropometry measures and prevalence of obesity in the urban adult population of Cameroon: an update from the Cameroon Burden of Diabetes Baseline Survey BMC Public Health, 6, 228 Kumanyika, SK (1993) Special issues regarding obesity in minority populations Annals of Internal Medicine, 119 (7 Pt 2), 650 4 Lee, CMY, Martiniuk, ALC, Woodward, M et al on behalf of the Asia Paci c Cohort Studies Collaboration.

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